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Professor George Litefoot was a pathologist in London during the 1880s and 1890s whose path intersected with the Doctor more than once.
His father was a brigadier-general who was involved in the punitive expedition to China in 1860. He lived in Peking as an attaché and George spent most of his childhood in China.
After his father's death in 1873, Litefoot returned to England. He also brought back the 51st century war criminal Magnus Greel's time cabinet, which had been disguised as a Chinese puzzle box and was a gift from Emperor Tongzhi to his mother.
In 1889, he was investigating several corpses related to Greel and the Tong of the Black Scorpion when he encountered the Fourth Doctor and Leela. He helped them with their investigations, and lent the Doctor a gun to kill the giant rats created by Greel. At the same time, Greel found out that Litefoot had the time cabinet and sent Mr Sin and his other servants to take it back.
Litefoot joined forces with Henry Gordon Jago to find where Greel escaped to. They followed him to the House of the Dragon, where they were captured by members of the Tong. The Doctor tried to help free them, but he was captured as well. During the final confrontation with Greel, Jago and Litefoot helped to distract Mr Sin.